Polycystic kidney disease or PKD is a genetic condition imputed to abnormal growth in the kidneys. Over time, such a sac-like membrane gets filled with blood. PKD is disparate to simple kidney cysts that usually grow later in life. First thing first, PKD is a noncancerous disease that, although it affects your kidney function abnormally, is nontransferable. Later in life, if such disease is not treated may cause you end-stage renal disease. Not only this, but PKD may also cause severe complications, such as problems with blood vessels in your brain and heart, cysts in the liver, high blood pressure, etc.
An individual with PKD can have kidneys five times that of their original size. So, it is important to treat it with the help of Polycystic kidney disease ayurvedic treatment. No allopathy treatment guarantees permanent recovery like Ayurveda does.
There are two different forms of PKD as distinguished by the age of onset and the pattern in which an individual receives the genes from parents.
Autosomal dominant PKD: This form of PKD is quite common. The signs and symptoms of this form of PKD appear later in life though genes are present from birth.
Autosomal recessive PKD: This form of PKD is a rare condition that occurs in newborns. The signs of ARPKD may appear at birth or in early infancy.
It is the mutations in the PKD1, PKD2, and PKHD1 gene that causes polycystic kidney disease.
When the mutations occur in either PKD1 or PKD2 gene, an individual may have autosomal dominant polycystic kidney disease. There are further two types of ADPKD. A genetic mutation in the PKD1 gene causes ADPKD type 1, and PKD 2 genetic mutations cause ADPKD type2. Such genes are held responsible for making proteins in the body. The mutations in the PKD1 or PKD 2 gene lead to the development of cysts in the kidneys. People with mutations in the PKD 2 gene, particularly women, have less severe complications than those with the PKD1 gene.
Autosomal recessive PKD, on the other hand, is caused by genetic mutations in the PKHD1 gene. Still, doctors or scientists do not know what causes the PKHD1 gene and resultant the generation of numerous cysts on the kidneys.
Yet, there are some cases that are not caused by genetic mutations. They are known to be acquired polycystic kidney disease. This form occurs in people who are already on hemodialysis for years. Polycystic kidney disease treatment is needed for such patients.
Inheritance
Most cases of PKD follow ADPKD pattern of inheritance. Those with ADPKD have only one copy of the gene (either PKD 1 or PKD 2) in each cell. This happens nearly in 90% of the cases, while 10% of cases result from a new mutation with no history of the disorder in their family.
Although one copy of the altered gene is sufficient to cause the disorder, an additional copy of the PKD1 or PKD2 gene makes cysts grow at an increasing rate. The rate at which cysts may grow depends on other factors as well.
People with an Autosomal recessive pattern may have two altered copies of the PKHD1 gene. Actually, the parents are not affected with PKD though they are the carriers of one copy of the altered gene.
The generalized symptoms that may appear with PKD include:
High blood pressure
Back or side pain
Blood in your urine
A feeling of fullness in your abdomen
Increased size of your abdomen due to enlarged kidneys
Headaches
Kidney stones
Kidney failure
Urinary tract or kidney infections
When to see a doctor
PKD may remain unnoticed for years without you even knowing it. If you have these signs, consult your doctor as soon as possible. In case if you have a first-degree relative, be it a parent, sibling, or child who has polycystic kidney disease, screening is essential. If possible, start with the polycystic kidney disease ayurvedic treatment at the earliest.
Polycystic kidney disease ayurvedic treatment
You can also have PKD cured with the help of Ayurveda. Ayurvedic remedies are helpful in curing the genetic flaws so that PKD can be terminated completely. This line of treatment even eliminates the need for dialysis when the kidney function declines due to the poor involvement of cysts in the kidneys.
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